fibrin$28052$ - definizione. Che cos'è fibrin$28052$
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Cosa (chi) è fibrin$28052$ - definizione

FIBROUS PROTEIN INVOLVED IN BLOOD COAGULATION
Fibrin modulating agents; Fibrinous; Fibrin polymer; Fibrin polymers
  • Composition of a fresh [[thrombus]] at microscopy, [[HE stain]], showing nuclear debris in a background of fibrin and [[red blood cells]].
  • From [[Fibrinogen]] to Fibrin with the help of [[Thrombin]] and [[Factor XIII]].
  • Cross-linking by thrombin and stabilization by activated factor XIII

Fibrinous         
·adj Having, or partaking of the properties of, fibrin; as, fibrious exudation.
Fibrin         
·noun An albuminous body, resembling animal fibrin in composition, found in cereal grains and similar seeds; vegetable fibrin.
II. Fibrin ·noun The white, albuminous mass remaining after washing lean beef or other meat with water until all coloring matter is removed; the fibrous portion of the muscle tissue; flesh fibrin.
III. Fibrin ·noun A white, albuminous, fibrous substance, formed in the coagulation of the blood either by decomposition of fibrinogen, or from the union of fibrinogen and paraglobulin which exist separately in the blood. It is insoluble in water, but is readily digestible in gastric and pancreatic juice.
fibrin         
['f??br?n, 'f?b-]
¦ noun Biochemistry an insoluble protein formed as a fibrous mesh during the clotting of blood.
Derivatives
fibrinoid adjective
fibrinous adjective

Wikipedia

Fibrin

Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platelets, forms a hemostatic plug or clot over a wound site.

When the lining of a blood vessel is broken, platelets are attracted, forming a platelet plug. These platelets have thrombin receptors on their surfaces that bind serum thrombin molecules, which in turn convert soluble fibrinogen in the serum into fibrin at the wound site. Fibrin forms long strands of tough insoluble protein that are bound to the platelets. Factor XIII completes the cross-linking of fibrin so that it hardens and contracts. The cross-linked fibrin forms a mesh atop the platelet plug that completes the clot. Fibrin was discovered by Marcello Malpighi in 1666.